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    How does VECTRA® 3D kill fleas and ticks on my dog?

    VECTRA® 3D protects because of the triple-action formula of Dinotefuran, Pyriproxifen, and Permethrin. These ingredients work together to kill fleas and ticks on contact and repel these dangerous parasites.
    Once they land on your dog, the parasites come into contact with the treated skin and hairs. The more they move on the dog to find a location to bite, the more they are exposed to the active ingredients of VECTRA® 3D and the sooner they are affected.
    In ticks, VECTRA® 3D causes what is known as a “hot foot” reaction. Sensors in the legs of these parasites are very sensitive to permethrin, which, following contact, makes the parasite physically compelled to crawl back up the fur, away from the skin of the dog, without biting.
    In fleas, VECTRA® 3D rapidly disrupts feeding behavior. Once the product has moved/translocated following administration, flea feeding is strongly reduced within just 5 minutes when compared to untreated dogs. Fleas are quickly knocked down and start falling off the animal without possible recovery. Thanks to the synergy between dinotefuran and permethrin, fleas are killed within 2 hours of contact.

    Can VECTRA® 3D be used on pets other than dogs?

    No. Do not use VECTRA® 3D on cats, or any other animal.

    Do parasites have to bite in order for VECTRA® 3D to work?

    No. VECTRA® 3D is able to either repel or kill parasites when they come into contact with your pet’s fur.

    Is it okay to apply VECTRA® 3D more than once a month?

    No, only apply VECTRA® 3D once in a 30-day period. It is not necessary for more frequent applications – VECTRA® 3D provides powerful protection against fleas and ticks for a full month.

    Should I remove ticks I see on my dog before applying VECTRA® 3D?

    Yes. The sooner ticks are removed from your dog, the better and you prevent the transmission of pathogens to your dogs. Use an appropriate tick removal device. Be sure to remove the entire body of the tick, including mouthparts. Once removed, destroy the tick.

    What should I do if my dog exhibits unexpected signs after VECTRA® 3D administration?

    Contact your veterinary surgeon immediately for advice.

    Does VECTRA® 3D control other parasites besides fleas and ticks?

    Yes. VECTRA® 3D is proven to protect your dog for a full month from other major vectors such as mosquitoes, sand flies and biting flies.

    What happens to the active ingredients once VECTRA® 3D has been applied?

    Following topical application of VECTRA® 3D, the active ingredients move/translocate from the application site to cover the entire body surface within the first few hours and remain for a month.
    After topical application of VECTRA® 3D, dinotefuran is partially absorbed through the dog’s skin, leading to systemic exposure – this absorption does not impact the product’s effectiveness.
    Some pyriproxyfen absorption through the skin may also occur.
    Permethrin from VECTRA® 3D is not knowingly absorbed through the dog’s skin.

    Is my cat at risk if I use VECTRA® 3D on my dog?

    To be at risk, your cat needs to ingest or be in contact with VECTRA® 3D. This can occur if your cat grooms a treated dog and if the application site is not dry yet. To prevent oral exposure of your cat to VECTRA® 3D, we recommend keeping treated dogs away from cats after treatment until the application site is dry. Cats should not be allowed to groom dogs at the application site until the product has dried. Seek veterinary advice immediately if this occurs.

    How does VECTRA® 3D control immature stages of fleas?

    Rather than being physically on your dog, immature stages of fleas are hidden in the environment of your home (often located where the pet sleeps). Flea eggs, as laid by adult fleas on your pet, fall off the animal and develop into these immature larval stages.
    Pyriproxyfen, is a highly potent insect growth regulator: it is active at a very low concentration. It disseminates from the treated dog (hairs, skin debris, dust, etc.) and by doing so is able to disrupts the development of the immature stages of the fleas in the environment. This kills immature fleas, thus preventing emergence of new adults. As demonstrated (Bouhsira et al., 2012), it also sterilizes adult female fleas that are exposed to treated dogs, which prevents egg laying.

    Are there possible interactions with other medicinal products?

    No, there are no known interactions.

    Can I brush my dog after applying VECTRA® 3D?

    Yes. VECTRA® 3D remains effective after repeated combing of dogs. However, to reduce your own exposure to the actives, it is recommended not to brush or comb your dog until the application site is dry.

    What should I do if my dog licks itself?

    Do not worry. VECTRA® 3D has been shown to be safe when ingested at up to 5 times the maximum dose on young dogs. However, to optimize the duration of efficacy of VECTRA® 3D, we recommend you to distract your dog after administration, while VECTRA® 3D dries.

    Is it okay for my pet to bathe or swim after applying VECTRA® 3D?

    Yes. VECTRA® 3D remains effective in controlling fleas and ticks for a full month, even if your pet immerses themselves fully in water through swimming or bathing. However, for full and sustainable efficacy, it is advised not to bathe or immerse your dog in water until the application site has fully dried. This may take up to several hours, but it is highly variable according to temperature and air exposure.
    In studies performed under controlled conditions, bathing at 48 hours after administration, and then subsequently at weekly intervals, showed no reduction in the product’s efficacy against fleas or ticks. To prevent environmental contamination, we recommend that treated dogs do not enter surface water sources (e.g. rivers, streams, sea) for 48 hours after treatment.

    When is the best time for VECTRA® 3D administration?

    We advise that you administer VECTRA® 3D at the end of the day or before taking your dog for a walk.
    Once applied, VECTRA® 3D moves/translocates onto the dog’s skin and can lead to unusual sensations for your pet. If your animal is distracted or sleeping while this phenomenon takes place, it will help make them more comfortable.
    If applied in the evening, the product will have time to dry during the night, thus reducing the possibility of human exposure.

    How quickly does VECTRA® 3D begin to work?

    Clinical studies have shown that in dogs treated with the active ingredients in VECTRA® 3D, flea feeding is reduced within five minutes and fleas are killed within the first few hours — 6 hours for previously untreated dogs with flea infestations (therapeutic use of the product) and 2 hours for dogs that have been treated previously (residual activity).
    VECTRA® 3D is effective against ticks 48 hours after it has been applied.
    Onset of activity is also rapid against flying insects. VECTRA® 3D repels sandflies, mosquitoes, and biting flies from just 24 hours after administration. VECTRA® 3D kills Stomoxys flies within 30 minutes and Aedes mosquitoes within 60 minutes of exposure to a treated dog.

    Does VECTRA® 3D control immature stages of fleas and ticks?

    Yes. Immature stages of ticks are more susceptible to active ingredients than adult forms. They are easier to kill.

    VECTRA® 3D contains the Insect Growth Regulator pyriproxyfen. It makes VECTRA® 3D truly effective against all immature stages of fleas for 2 months after administration.

    What age and body weight does my dog need to be before I can apply VECTRA® 3D?

    VECTRA® 3D can be used on puppies as young as 7 weeks of age and weighing above 1.5 kg.

    What are the contraindications of VECTRA® 3D?

    VECTRA® 3D is entirely contraindicated for use on cats. This is due to their unique physiology and inability to metabolise permethrin.
    VECTRA® 3D must not be used on cats. If applied to a cat, or if ingested by a cat that actively grooms a recently treated dog, VECTRA® 3D may have serious and harmful effects. If this occurs, contact your veterinarian immediately.
    VECTRA® 3D is also contraindicated in animals with known hypersensitivity to any of the active substances or to any of the excipients.

    What if VECTRA® 3D comes into contact with delicate fabrics or materials?

    VECTRA® 3D can stain some susceptible fabrics and other materials. We recommend administering VECTRA® 3D outside or in a room away from susceptible surfaces. You should wait until the application site is dry before allowing your dog to come into contact with susceptible materials or surfaces. Make sure that your dog does not shake after administration. If VECTRA® 3D does come into contact with delicate materials then use an absorbent cloth to remove as much of the product as possible before cleaning the surface appropriately.

    If a cat is accidentally exposed to VECTRA® 3D, what should I do?

    If a cat is accidentally administered VECTRA® 3D, or if it is exposed to VECTRA® 3D from a treated dog the following is recommended:

    If administered directly to a cat, bathe the cat with washing up liquid to remove any residual product. Dry the cat well and maintain body temperature. Seek veterinary advice immediately.

    If VECTRA® 3D gets in my eyes or on my skin, what should I do?

    In case of human exposure contact your doctor for treatment advice. Having the product container or label with you when calling your doctor, or going for treatment, is also advisable.
    If in the eyes, hold eye open and rinse slowly and gently with water for 15 to 20 minutes. Remove any contact lenses. Call a poison control center or doctor for treatment advice.
    If swallowed, call a poison control center or doctor immediately for treatment advice. Have a person sip a glass of water if able to swallow.
    Do not induce vomiting unless told to do so by a poison control center or doctor. Do not give anything to an unconscious person.
    If on the skin, take off contaminated clothes. Rinse the skin immediately with plenty of water for 15 to 20 minutes.
    Call a doctor immediately for treatment advice.

    What if VECTRA® Felis gets in contact with fabrics or house material?

    VECTRA® Felis can stain some susceptible fabrics and other materials.

    This is why you should wait until the application site is dry before allowing your cat to come in contact with your sofa or other susceptible surfaces.

    We also recommend administering VECTRA® Felis outside or in a room where susceptible surfaces are not close to your cat.

    Make sure that your cat does not shake himself after administration. If contact with material happens, immediately absorb as much as possible of the product with absorbent paper and clean.

    If VECTRA® Felis get in my eyes or on my skin, what should I do?

    In case of Human exposure to VECTRA<sup>®</sup> Felis, contact your doctor for treatment advice. Having the product container or label with you when calling your doctor, or going for treatment, is also advisable.
    If in the eyes, hold eye open and rinse slowly and gently with water for 15 to 20 minutes. Remove any contact lenses. Call a poison control center or doctor for treatment advice.
    If swallowed, call a poison control center or doctor immediately for treatment advice. Have a person sip a glass of water if able to swallow.
    Do not induce vomiting unless told to do so by a poison control center or doctor. Do not give anything to an unconscious person.
    If on the skin, take off contaminated clothes. Rinse the skin immediately with plenty of water for 15 to 20 minutes.
    Call a doctor immediately for treatment advice.

    What should I do if my cat licks itself?

    Do not worry.

    VECTRA® Felis has been shown to be safe when ingested at up to 4 times the maximum dose on young cats without adverse effect other than salivation and vomiting.

    However, to optimize the duration of efficacy of VECTRA® Felis, we recommend you to distract your cat after administration, while VECTRA® Felis dries.

    Why should I worry about immature fleas?

    While immature fleas do not feed on the animals, they represent a large proportion of the flea population and will develop into new adults ready to feed on your pet.

    Can VECTRA® Felis be used on pets other than cats?

    No. Do not use VECTRA® Felis on any other animal.

    Can I brush my cat after applying VECTRA® Felis?

    Yes. VECTRA® Felis remains effective after repeated combing of cats.

    However, to reduce your own exposure to the actives, it is recommended not to brush or comb your cat until the application site is dry.

    Is it okay to apply VECTRA® Felis more than once a month?

    No, only apply VECTRA® Felis once in a 30-day period.

    Unless recommended by your veterinarian, it is not necessary for more frequent applications.

    VECTRA® Felis provides powerful protection against fleas for a full month.

    Is it okay for my pet to bathe or swim after applying VECTRA® Felis?

    This has not been tested. To ensure efficacy and to protect the environment, it is recommended not to bath or immerse your cat in water until the application site is dry.

    Do parasites have to bite in order for VECTRA® Felis to work?

    No. VECTRA® Felis kills parasites through contact with your pet’s fur. No biting necessary.

    Why should I worry about fleas on my cat?

    Fleas are small parasites that feed on blood and multiply very quickly. When they bite your cat, they can transmit dangerous diseases to your pet and to your family.

    How quickly does VECTRA® Felis begin to work?

    Fleas are killed (>95%) within 2 hours

    What age does my cat need to be before I can apply VECTRA® Felis?

    VECTRA® Felis can be used on kittens as young as 7 weeks of age and at least 0.6 kg bodyweight.

    When is the best time for VECTRA® Felis administration?

    We advise you to administer VECTRA® Felis at the end of the day.

    Are there possible interactions with other medicinal products?

    No, there are no known interactions.

    What should I do if my cat licks itself?

    Do not worry. VECTRA<sup>®</sup> Felis has been shown to be safe when ingested at up to 4 times the maximum dose on young cats without adverse effect other than salivation and vomiting. However, to optimize the duration of efficacy of VECTRA Felis<sup>®</sup>, we recommend you to distract your cat after administration, while VECTRA<sup>®</sup> Felis dries.

    How does VECTRA® Felis kill fleas on my cat?

    VECTRA® Felis protects because of the double-action formula of dinotefuran and pyriproxifen. These ingredients work together to kill fleas on contact.